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Thus, if several doses are administered over a short time frame (e.g., less than 24 hours), the phenobarbital level can be estimated with reasonable accuracy

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In this Review, we explore both recently discovered compounds and established envelope-targeting antibiotics, including compounds that target Gram-positive bacteria, more complex Gram-negative bacteria and mycobacterial pathogens, shedding light on this still clinically underexplored and vital therapeutic approach