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This Review provides an overview of UPS-mediated proteostasis, focusing on the involvement of the UPS in renal physiology and pathophysiology.

This has raised concerns about their impact on cancer risk, spurring extensive research

The study challenges the notion of redox compartmentalization in MLOs, suggesting that their redox environment mirrors that of their surroundings, likely due to the lack of physical barriers and similar partitioning of GSH and GSSG.
