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[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Vacca M., Calabrese F.M., Loperfido F., Maccarini B., Cerbo R.M., Sommella E., Salviati E., Voto L., De Angelis M., Ceccarelli G., et al

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Furthermore, IPP-derived CoQ can be converted into ubiquinol (CoQH 2 ) by ferroptosis suppressor protein 1 (FSP1) to inhibit lipid peroxidation and ferroptosis [51], and FSP1 can act in parallel to the GPX4 pathway to inhibit ferroptosis in cancer cells [52]

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Drug Discovery 2021, 20 (5), 362 383, DOI: 10.1038/s41573-021-00139-y142Strategies for delivering therapeutics across the blood-brain barrierTerstappen, Georg C