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Dry skin is itchy because, when its outermost layer lacks sufficient moisture, the skin barrier becomes weak

Crit Care 28(1):292

110 SchubertD.PiaseckiD

According to a recent study (144), the lncRNA HEPFAL acts on SLC7A11 and reduces its expression, resulting in a decrease in the amount of cystine transported into the cell and, as a result, a decrease in the intracellular GSH level, which effectively inhibits the iron apoptosis function of GPX4 and, ultimately, iron apoptosis in tumor cells

Simon M, Wang MX, Ismail O et al (2022) Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid plaque formation in mice