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Glutathione may affect skin pigmentation by inhibiting an important enzyme called tyrosinase during the formation of melanin, the pigment found in hair and skin

Pestic Biochem Physiol 179:104959 Adams JC, Seed B, Lu N, Landry A, Xavier RJ (2009) Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress

IAA, a pathway for indole production by tryptophan metabolism in Escherichia and others, was shown to be effective in the production of indole via the AHR signaling pathway [182] in VEGF-treated human umbilical vein endothelial cells (HUVEC) exerts anti-angiogenic effects and is able to inhibit VEGF receptor-2 and eNOS phosphorylation in HUVEC cultures with reduced NO production and decreased vasodilatory capacity [183]

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