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For these reasons, solutions are sought that will allow for the safe continuation of treatment supplementing cobalamin deficiency

PubMed Malinda KM, Sidhu GS, Mani H, et al

Being deficient in B12 is not only a very common deficiency

Insulin resistance: Patients with metabolic dysfunction, including pre-diabetes or difficulty managing blood sugar, tend to see meaningful improvement in metabolic markers alongside body composition changes

Brief exposure during transport (up to 2 hours unrefrigerated) is generally acceptable, but repeated temperature cycling degrades stability and should be avoided
