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Mutual interactions between mast cells, basophils, eosinophils, and macrophages, and the secreted mediators (cytokines, chemokines, enzymes, and ROS) can damage the epithelium of intestinal villi (185)

"Meta-analysis of the risk factors for urinary tract infection in children"

KSS is a severe syndromic variant of CPEO that progresses to multisystemic effects due to large deletions in the mtDNA of unknown cause

This is particularly significant, as mitochondrial diseases often result in severe neurological impairments
