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Contributing to the neural degeneration seen in vitamin B12 deficiency is the reduced synthesis of S-adenosylmethionine (SAM

Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes

While reductions in protein aggregate volume were observed in some cases, this clearance did not consistently translate into cognitive improvement [6, 7]

Sirtuins as potential targets for metabolic syndrome

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