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The presence of lipopolysaccharides and endotoxins from gram-negative bacteria contributes to hepatic fibrosis progression (322, 323) (Symbols: , increased abundance

Although -oxidation is impaired in the setting of VPA toxicity, this metabolite has a prolonged elimination half-life and could be responsible for the prolonged coma that is sometimes observed despite the normalization in plasma VPA concentrations [17, 18]

In contrast, fungal biofilms, such as those formed by Candida albicans, produce a matrix rich in -1,3-glucan, mannan, lipids, proteins, and DNA [15]

Limited intake of sources rich in B vitamins, such as meats, leafy greens, and fortified grains, due to selective eating patterns or food sensitivities[40]

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