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Description
Prev Med
Published preclinical studies used intraperitoneal injection in rodents, which bypasses the subcutaneous absorption variability human protocols face
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The angiogenesis and disruption of liver vascular architecture have been linked to progression to cirrhosis and liver cancer in chronic liver diseases, which contributes to both increased hepatic vascular resistance and portal hypertension and decreased hepatocyte perfusion [119,120,121]
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