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Compared to oral and intravenous administration, pulmonary drug delivery has the advantages of local lung targeting, high local drug concentration and rapid onset of action, low systemic distribution and toxicity, avoided degradation in the gastrointestinal tract and hepatic firstpass metabolism, and good patient compliance without using needles [4, 5]

Dimesso, L

J Physiol (Paris) 94:7781 Christensen S, Riis A, Nrgaard M, Thomsen RW, Tnnesen EM, Larsson A, Srensen HT (2006) Perforated peptic ulcer: use of pre-admission oral glucocorticoids and 30-day mortality

This is different from freezing AFTER reconstitution (which is harmful)

doi: 10.1111/ejn.14913, 84 HockleyA.ShoreS