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Produced by the liver and found in almost every human cell, it protects the body from oxidative stress caused by free radicals, said Dr

Interaction between NO and O 2 generates a set of oxides with a higher nitrogen oxidation state (the so-called autoxidation), among which N 2 O 3 is considered as the major nitrosylating agent contributing to the formation of protein nitrosothiols and nitrite ion

In the stable form of FDG-6-phosphatate (FDG-6-P), the fluorescence intensity is detected, reflecting the activity of GLUT of the tissue under test [248]

We conducted constrained optimizations (see Methods ) for (i) the interaction pathway targets identified by the differences in metabolic adaptability (same as the input for TF enrichment analysis above), (ii) the interaction pathways potentially regulated by ESRRA (above), (iii) parameters corresponding to arterial blood glucose and ketone levels (mimicking dietary factors), (iv) parameters corresponding to arterial blood lactate levels (mimicking exercise factors), and (v) total NAD-pool parameters in neurons and astrocytes (mimicking NAD-related supplementation)