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Vukojevic et al., 2018
2013;17(4):52531 Hawley MA
10.3390/ijms25021211 2 AdamsL.NoutsiasM.BigalkeB.MakowskiM
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Approaches that suppress lactate production, such as using PDK inhibitors (DCA and thiamine), have been demonstrated to alleviate organ damage and mitigate ferroptosis in sepsis by reversing the pathological Warburg effect-like state, thereby improving mitochondrial function and reducing ROS accumulation (189,190)
