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Just honest, effective treatment

In patients already receiving an opioid analgesic, prescribe a lower initial dose of the benzodiazepine or other CNS depressant than indicated in the absence of an opioid, and titrate based on clinical response

"She's such a hard worker and can do whatever she wants in water polo

Blood 94:127a, 1999

Nicotinamide riboside (NR), a small NAD+ precursor, efficiently enters cells and is reliably converted into NAD+, making it a smarter way to boost NAD+ levels
