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Pharmacologic Therapy: Treatment strategies include duloxetine, tricyclic antidepressants (TCAs), anticonvulsants, compounded topical products, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioid therapy ( TABLE 2 )
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From 13( S )-HpODE, two hydroxy-epoxides possessing an epoxide at the 12(13)-position and a hydroxy group at the 9- or 11-position are created, along with their corresponding ketones
(See Supplementation Protocol Section)
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