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Usage : Consult with a healthcare provider before adding milk thistle to your supplement regimen

270 In addition, a recent study showed that short-chain fatty acids can act as ligands of G-protein-coupled receptors (GPCRs), such as GPR41, GPR43, and GPR109A, to activate PKC that can in turn phosphorylate ZO-1 in order to increase intestinal barrier function

doi: 10.1080/21645515.2021.2002083

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