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CF is supported by T32DK128781 from the NIH
Studies in 3D (tumor spheres) have confirmed that HTX attenuates the phenotype of CD133 + glioma stem cells, limiting self-renewal capacity and cell migration [112]
High transcytosis of melanotransferrin (P97) across the bloodbrain barrier
It is also possible that the serine requirement of these malignancies can be partially met through exogenous serine uptake
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