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Description
Modulating FAO presents a promising strategy for addressing diseases associated with dysregulated fat and cholesterol metabolism, particularly in macrophages, as highlighted in several studies
Interface Sci
2021;14:e202000219
This can now undergo one cycle of oxidation to yield 4 Z -10:1-CoA, which is acted upon by an acyl-CoA dehydrogenase to produce 2 E ,4 Z -10:2-CoA before this in turn is the substrate for an NADPH-dependent 2,4dienoyl-CoA reductase to generate 3 E -10:1-CoA
[DOI] [PubMed] [Google Scholar] 114.El-Komy M., Shalaby S., Hegazy R., Abdel Hay R., Sherif S., Bendas E
