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PARKINSON'S DISEASE The brains of patients with Parkinson's disease exhibited a reduction of GSH, selective to the substantia nigra (SN)

Two other mu class members, GST M5-5 and the polymorphic GST M1-1, gave specific activities of 58 and 57.8 mol min 1 mg 1 , respectively

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This difference is likely explained by IPA's algorithm, which relies on a pattern of protein expression that is consistent with a specific direction of upstream regulator activity to calculate a z-score
