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Furthermore, this integrated approach demonstrated immunomodulatory effects characterized by elevated IL-2 with concurrent reduction in the levels of TGF-, IFN-, and interleukins (IL-23, IL-4, and IL-5), and improved immune function, as evidenced by increased CD4 + and CD4 + /CD8 + ratios [120, 122]

Veerbeek JM, Langbroek-Amersfoort AC, van Wegen EEH, et al

Review: soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

Muthuramalingam et al

As the hair follicle contains ECS and cannabinoid-responsive receptors, coupled with the evidence of cannabinoid deposition within the fiber followed by cannabis consumption and topical application, there may be potential to use compounds like CBD to treat certain hair disorders