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We've guided research teams through this exact protocol design question dozens of times

Notably, the highest dose tested (54 mg) showed increased gastrointestinal event frequency compared to lower doses, suggesting a dose-relationship for this effect category

Nature 562, 578582 (2018)
Bruising and soreness usually resolve within 35 days and don't indicate serious complications

The good news is that the injections are safe, virtually painless, and have a very minimal possibility of causing side effects
