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For example, wild-type DA neurons grafted into the striatum of mice overexpressing human -synuclein accumulated more host-derived -synuclein upon microglia depletion than in control hosts (George et al., 2019)

What It Is Class: Long-acting amylin receptor agonist Origin concept: Based on the endogenous peptide amylin (co-secreted with insulin from pancreatic ?-cells), with structural modifications to improve stability and half-life

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