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10.1038/nature22395 Nature 214 SainiU.NaiduS.ElNaggarA

Steffens J, Kosharskyy B, Hiebl R, Schnberger B, Rttger P, Loening S

330,331 TMAO inhibitors (e.g., ALG-05, which targets tryptophan indole lyase) curb IS production, easing fibrosis, whereas tight junction enhancers (e.g., chitosan oligosaccharide [COS]) activate intestinal CaSR/AMPK pathways, reducing systemic inflammation and oxidative stress in prediabetes, with COS also balancing mTOR-autophagy dynamics in renal cells

Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling

Glucose, 2 mg/g body weight (G8769
