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Researchers also examine peptides for their potential utility in developing advanced diagnostics, delivery systems, and laboratory models

Given the interconnected relationship among biological aging hallmarks, manipulating one has potential to impact others

Also, elevated cholesterol levels augment the activity of both - and -secretases, enzymes essential for A generation, thereby further exacerbating AD pathology (Marzolo & Bu, 2009)

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In addition to their well-characterized catalytic activity, there is evidence that GST isoenzymes also participate in regulating the expression of mitogen-activated protein kinases, and promote S-glutathionylation of cysteine residues in target proteins (19)