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[PubMed] [Google Scholar] 20.Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, et al

There is no clinically established dose of B12 that boosts metabolism in non-deficient individuals, because extra B12 does not produce that effect

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For patients diagnosed with a vitamin B12 deficiencyespecially when caused by problems with absorption in the digestive tract (such as pernicious anemia, certain gastrointestinal conditions, or after specific surgeries)oral supplements may not be effective