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Disulfide-containing linkers are primarily linked to maytansinoid payload classes, and the reactivity of disulfide bonds can be regulated by steric hindrance: alpha methyl substitution significantly affects reduction rate and resistance to thiol-disulfide exchange force
The authors found that the obtained lipid carriers were not cytotoxic in vitro, retained -lipoic acid, and released it within 72 h [101]
Cakman I, Kirchner H, Rink L
The influence of Hcy on LBW, however, is clearer [146]
Chapter four - recent developments in targeting neuroinflammation in disease
