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What was striking about the T-cell response in the HCWs with abortive infection was the enrichment for T cells targeting the conserved nonstructural proteins of open reading frame 1ab (ORF1ab), which make up the core of the RTC [67]

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In the 40 M pretreatment group, levels remained high even in the absence of NFT and showed only a modest increase in response to the re-addition of NFT (Fig

While DPP-IV is effective at cleaving proline bonds, it is an exopeptidase , meaning it can only snip amino acids from the external ends of the long protein chain