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Description
Graphical Abstract Similar content being viewed by others Introduction Metformin, the primary treatment for type 2 diabetes, is largely well tolerated but can cause vitamin B 12 deficiency in 5.822% [1, 2] of patients
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Keep the pens in the original carton to protect them from direct sunlight and extreme temperatures

If you have limited dietary intake of B 12 and experience symptoms listed in box 1, you might have B 12 deficiency

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