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From this perspective, neurons may satisfy their increased energy needs directly through accelerated glucose uptake and oxidative phosphorylation, with astrocyte-derived lactate playing a minimal role as an oxidative fuel under normal physiological conditions
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One of the great advantages of glutathione for depression is that it can be used without any negative side effects, such as the weight gain associated with most pharmaceutical antidepressants
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5-Lipoxygenase plays an essential role in 4-HNE-enhanced ROS production in murine macrophages via activation of NADPH oxidase
