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In our study, both doses of levosimendan were associated with significant downregulation of NFK-, TNF-, and Il-6 expressions

While several subtype-specific therapeutic approaches have been identified for SCLC 36,37,38,39,40,41 , recent evidence suggests that SCLC subtype intratumoral heterogeneity may evolve as a consequence of subtype plasticity 5 highlighting the need to devise therapies targeting SCLC plasticity rather than isolated molecular subtypes

and methylphenyltetrahydropyridine, which inhibits complex I in the respiratory chain (200)

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2017;114:E8294E8303