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doi:10.1016/j.nutres.2016.03.010 Dzupina A, Pella D, Zenuch P, et al
Emerging research suggests additional roles in immunoregulation and carcinogenesis inhibition (52)
In the microenvironment of solid tumors, hypoxia has been shown to stimulate autophagy in tumor-associated blood vessels which in turn can alter metabolic pathways and surface markers of endothelial cells (Verhoeven et al., 2021)
Glycolysis further fuels the pentose phosphate pathway (PPP) which produces NADPH
