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In aging mice this could mean a failure to adapt to aging-related bioenergetics deficits with less flexibility in fuel use in E4s which is further aggravated by female sex

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The role of ME2 in these types of cancers relates to its functions in mitochondrial biogenesis

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The effect of omega-3 unsaturated fatty acids on non-alcoholic fatty liver disease: A systematic review and meta-analysis of RCTs
