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Gut immune cell trafficking: Inter-organ communication and immune-mediated inflammation
Using powerful genome scanning techniques, many major genetic factors that predispose to type II DM have been identified ( Table 10-6 )

[DOI] [PubMed] [Google Scholar] 37.Martin M.S., Dutt K., Papale L.A., Dube C.M., Dutton S.B., de Haan G., Shankar A., Tufik S., Meisler M.H., Baram T.Z., et al

As important risk factors for NAFLD such as obesity and type 2 diabetes are increasing in prevalence this could explain the marked increase in numbers of individuals with NAFLD[9]

120 Crosstalk of NF-B signaling with JAK-STAT signaling Janus kinase 2 (JAK) binds non-covalently to cytokine receptors, mediates the tyrosine phosphorylation of the receptor, and recruits one or more signal transducer and activator of transcription (STAT) proteins
