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Description
Occupational exposure to carcinogens in industries such as chemicals, dyes, rubber manufacturing, and petroleum processing is the second leading risk factor for urothelial bladder cancer (UBC) after smoking, accounting for approximately 20% of cases, primarily in industrial regions
Kelch-like Ech-associated Protein-1 (KEAP1) keeps Nrf2 tethered in the cytoplasm, where it is degraded in an unstressed state by the ubiquitinproteasome system
K.ZelicM.HanY.TeepleE.ChenL.SadeghiM.et al (2023)
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Aging Cell 19(12):e13268
