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Hsa_circ_0066523 promoted proliferation and osteogenesis of BM-MSCs by inhibiting PTEN [163]

84 All of the ROS cause an imbalance of redox state within the inflamed tissue, resulting in the activation of NF-B and the transcription of several pro-inflammatory cytokines including TNF, IL-1 and IL-6, which have key roles in the progression of RA and therefore are therapeutic drug targets