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The prospective study that followed 4,007 individuals with or without cardiovascular disease for a three-year period found baseline concentrations of circulating TMAO to be positively correlated with incidence of death, nonfatal myocardial infarction, and stroke described as major adverse cardiac events (MACE) (23)

This helps maintain effectiveness and product quality

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The inclusion of folic acid and vitamin D also supports bone health and cardiovascular function, rounding out a truly comprehensive supplement

All of this together ends up accounting for roughly 10% of our TEE