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10.1053/j.gastro.2013.02.042 12 MynsterK

The data collected in an FIH study in most respects are no different from any clinical trial and consists of physical examinations, monitoring of vital signs, laboratory data, including hematology, chemistry and urinalysis, and electrocardiograms (ECGs) collected at baseline and at various times during the conduct of the clinical trial

doi: 10.3390/molecules25030609 5

Compared with Actilyse, it has a longer half-life (22 minutes versus 3.5 minutes), about 15 times greater fibrin selectivity and 80 times greater resistance to plasminogen activator inhibitor-1 (PAI-1), an inhibitor of thrombolysis

Lindner, M
