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Although astrocyte reactivity is likely in the first instance to be targeted at maintaining CNS homoeostasis and circuit functions, various mechanisms could alter astrocyte functions in potentially detrimental ways, including (i) persistent reactivity may contribute to chronic neurodegenerative disorders or chronic inflammation, (ii) ageing and cellular senescence which may alter and reduce astrocyte functional capacities, or (iii) genetic mutations in diseased astrocytes or polymorphisms may alter normal astrocyte functions or responses

In contrast, monoglycerides and fatty acids with longer chains undergo reassembly into triglycerides within the cells of the small intestine [15]

The dawn of a new era of targeted lipid-lowering therapies

From the time of its foundation until the Revolution broke out, its history, like that of the other New England settlements, exhibits the ebbing and flowing of the tide of prosperity, under the influences of the laws of the supreme government and the pressure of Indian hostilities

Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism