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demonstrated that the administration of 50 mg/day of zinc in patients with PCOS for 8 weeks significantly reduced hirsutism, alopecia, MDA, and CRP

AAV-mediated acute knockdown of Gpr146 confirms its role in promoting hepatic steatosis and adiposity To further validate the regulatory role of GPR146 in hepatic lipid accumulation and to rule out the possibility that the phenotypes observed in germline knockout mice result from developmental compensation, we employed an AAV-mediated approach to acutely knock down Gpr146 in adult mice

in the liver

Radmann V, Sousa RO, Weinert C, Jordo HWC, Carlos FS

C: Promotes body fat reduction and preserves lean muscle tissue