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Islets isolated from WT and GCGR-KO mice were loaded with the cytoplasmic Ca 2+ indicator Fluo-4 AM, and cytoplasmic Ca 2+ concentration responses to stimulation were recorded by confocal time-lapse imaging (Fig
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Dose ranges come from allometric scaling (using a math formula to translate a mouse mg/kg dose into a human dose) and from research community use
