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doi: 10.3389/fmicb.2014.00627 63 SerranoILuqueAAranJM

1 XPO-1 inhibitor therapy The upregulation of XPO1 inactivates tumor suppressor anti-neoplastic function, facilitating the transport of tumor suppressor proteins from the nucleus to the cytoplasm

Only few proteins passed this stringent cutoff, including Cntfr, the immunoglobulin superfamily member 8 (Igsf8), the integral membrane protein 2B (Itm2b) and the heat shock 70 kDa protein 13 (Hspa13)