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Simultaneously, when the Bcl-2/Bax imbalance disrupts the TJ proteins between alveolar epithelial cells, it directly or indirectly induces the apoptosis of alveolar epithelial cells, leading to the destruction of the alveolar epithelial barrier and increased permeability, which ultimately causes alveolar edema, alveolar collapse and refractory hypoxemia
Med 2012, 745483
doi: 10.1021/acs.jproteome.6b00374 52 HughesH
