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Hepatic toxicity and endocrine disruption further compound the systemic burden of AAS misuse

Research is ongoing and model-dependent

Specifically, one node represents one 13 C-labeled metabolite, while an edge represents that two labeled metabolites shared similar isotopologue patterns and MS/MS spectra (i.e., structural similarity)

BPC-157 is a pentadecapeptide consisting of 15 amino acids

Future studies using other transgenic mouse models will be useful in determining the exact path-way by which paracetamol causes liver damage and may therefore provide novel therapeutic strategies by which to reverse liver damage in patients who present late after paracetamol overdosage