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In the future, integrating AI models with organoid platforms and ctDNA liquid biopsy systems is expected to form a closed-loop personalized metabolic treatment system, comprising diagnosis prediction feedback adjustment

ShahtoutJLEshimaHFerraraPJMaschekJACoxJEDrummondMJet al

Although current research lacks evidence linking EVs and SPM in resolving intestinal inflammation, we can hypothesize that encapsulating SPM within EVs for targeted delivery to critical sites may modulate inflammatory pathways

Pathologically, membrane depolarization ( 25 mM to form membrane-associated condensates at microdomains of the mitochondrial inner membrane, which are enriched with ANT and CK-MT

29 This affect is because the glycoprotein rich mucus layer covering the intestinal epithelium is the first line of defense against symbiotic microorganisms and invading pathogens