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Not sure that any actual weight loss has happened yet

Most clinical trials have shown it is well accepted by most patients and the side effects have mostly been negligible and very few have occurred

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The STEP-1 trial tested the effect of high-dose semaglutide to produce weight loss in people with obesity who do not have diabetes

Specifically, those with plasma homocysteine levels greater than 14 mol/L had nearly double the risk of developing Alzheimer's disease (71)