glutathione reductase with nadph Measuring the rate of consumption by in the cytosol and mitochondria PDF] Inhibition of Schistosoma mansoni

& Wadhwa, P

Currently, most studies and therapeutic agents focus on a single type of cell death, whereas opportunities related to other cell death pathways are typically overlooked

Perhaps the clearest set of mechanistic studies of ketones in a specific disease state has shown that oxidation of BHB in cardiomyocytes to generate energy is an adaptive mechanism that supports cardiac function in preclinical heart failure models [70,71,72] and in small human physiology studies in healthy individuals and in heart failure patients [70, 73]

this effect may drastically exacerbate symptoms in patients with G6PD deficiency

PMID 1900793