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In this perspective, we discuss novel aspects of signaling pathway activation in the context of inflammation and oxidative stress, and the broad view of potential effective pharmacotherapies that target the underlying mechanistic disease process in COPD

Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model

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Appl Physiol Nutr Metab 32(6):11241131 Gomez-Cabrera MC, Via J, Ji LL (2009) Interplay of oxidants and antioxidants during exercise: implications for muscle health

( A-B ) Violin plots of myeloid peripheral blood mononuclear populations (PBMCs) plotted by group as percentages of respective parent populations (gating schemes detailed in Extended Data Fig