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The strongest support comes from clinical evidence focused on treating vitamin B12 deficiency, not from general wellness claims What science supports The NIH Fact Sheet for Health Professionals shows that intramuscular B12 injections are effective at raising blood B12 levels and correcting deficiency

To control for the potential impact of stress induced by islet isolation and shipment, we performed immunostaining on islets that were fixed at the time of receipt (baseline)

Effect of supplementation with cobalamin carried either by a milk product or a capsule in mildly cobalamin-deficient elderly Dutch persons

Typically, a shoulder injection can relieve pain for several months

Comment: A few commenters argued that the measure itself is not actually a reflection of an agency's quality, and that just asking a person if they are up to date on their vaccination does not improve vaccination uptake, infection control, nor does it provide context for their answers or meaningful data for quality of care or outcomes