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FDA crackdown on compounding pharmacies (2023-2024) What happened: FDA increased scrutiny of compounded semaglutide Concerns about shortages vs compounding exemptions Some compounding pharmacies received warning letters Impact: Harder to get compounded versions of FDA-approved drugs Some clinics stopped offering certain peptides Shifted more toward truly non-approved peptides Takeaway: Regulatory environment tightening around compounded versions of FDA-approved drugs

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The evidence that gastric pentadecapeptide BPC 157 acts as a potent kinase inhibitor of VEGF and MAPK signaling and an inhibitor of melanoma cell growth in vitro [95] should be taken along with further evidence