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Example: 5mg peptide + 2ml water = 2,500mcg/ml concentration If you need 250mcg per dose: 250mcg 2,500mcg/ml = 0.10ml to inject More water = lower concentration = larger injection volumes

Estimates carry 20% uncertainty

It is easy to feel overwhelmed when one online forum suggests one ratio while your vial label seems to suggest another

In the UK, hydroxocobalamin 1 mg intramuscular injection is used: Without neurological involvement : 1 mg three times weekly for two weeks, then maintenance of 1 mg every two to three months With neurological involvement : 1 mg on alternate days until no further improvement in symptoms, then maintenance of 1 mg every two months Lifelong maintenance is required for pernicious anaemia or other irreversible causes of deficiency Oral B12 supplementation may be appropriate for diet-related deficiency in patients without neurological symptoms and with adequate absorption capacity
